Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609897 | 0.88 | NPC1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8612739 | 0.81 | NPC1 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8610635 | 0.80 | NPC1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8612806 | 0.73 | NPC1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8612803 | 0.72 | NPC1 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8553789 | 0.70 | NPC1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8553787 | 0.70 | NPC1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8612736 | 0.69 | NPC1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8303819 | 0.66 | NPC1 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL27907042 | 0.65 | ALDH1A1 (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | claimed |
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |