Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPM1B | O75688 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74396 | 0.97 | TP53 (0.56) | TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL2948892 | 0.97 | TP53 (0.56) | TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL2200767 | 0.97 | TP53 (0.56) | TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL244740 | 0.97 | — | — | |
| Methyl Alcohol SCHEMBL27845135 | 0.94 | TP53 (0.54) | TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL6271997 | 0.94 | — | — | |
| Ethylene SCHEMBL27716391 | 0.92 | — | — | |
| Ethylene SCHEMBL11226332 | 0.92 | TP53 (0.52) | TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL10681039 | 0.89 | TP53 (0.50) | TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL4547605 | 0.89 | TP53 (0.55) | TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656334-B1 | Process for the production of cyclohexanedimethanol, with preponderance of the trans-isomer | EASTMAN CHEM CO (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0656338-B1 | Vapour phase hydrogenation of esters or lactones to hydroxy compounds | EASTMAN CHEM CO (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0656337-B1 | Process for the production of 1,4-cyclohexanedimethanol | EASTMAN CHEM CO (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0656334-A1 | Process for the production of cydohexanedimethanol, with preponderance of the trans-isomer | EASTMAN CHEMICAL COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0656337-A1 | Process for the production of 1,4-cydohexanedimethanol | EASTMAN CHEMICAL COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0656338-A1 | Vapour phase hydrogenation of esters or lactones to hydroxy compounds | EASTMAN CHEMICAL COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| US-5395986-A | Hydrogenation of dialkyl cyclohexanedicarboxylate using copper or group VIII compound catalysts; high trans configuration to cis ratio | EASTMAN CHEMICAL COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| US-5395987-A | Hydrogenation of ester | EASTMAN CHEMICAL COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| US-5395991-A | Regeneration of hydrogenation catalyst | EASTMAN CHEMICAL COMPANY (US) | 1995-03-07 | — | — | US | disclosed |