SCHEMBL8611034

SCHEMBL8611034

CCCCC(CC)CSP(=O)(O)S(=S)(=S)CC(CC)CCCC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 4/20 0.37
FDPS P14324 6/20 0.36
CA2 P00918 4/20 0.35
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 3/20 0.33
ATM Q13315 1/20 0.33
MAPK1 P28482 1/20 0.32
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467475 0.81 CYP3A4 (0.47) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL2583732 0.77 CYP3A4 (0.47) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL9154488 0.76 CYP3A4 (0.46) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL7539306 0.74 CYP3A4 (0.44) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL4446174 0.74 ALDH1A1 (0.47) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL8467900 0.74 ALDH1A1 (0.47) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL15153014 0.73 ALDH1A1 (0.45) CYP3A4L3MBTL1ALDH1A1FDPSCA2
Phosphine SCHEMBL27074301 0.73 ALDH1A1 (0.45) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL27296353 0.73 ALDH1A1 (0.45) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL27324354 0.73 ALDH1A1 (0.45) CYP3A4L3MBTL1ALDH1A1FDPSCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524942-B1 METHOD OF SYNTHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS LYNX THERAPEUTICS INC (US) 1998-04-15 EP disclosed
US-5292875-A Method of synthesizing sulfurized oligonucleotide analogs LYNX THERAPEUTICS, INC. (US) 1994-03-08 US disclosed
EP-0524942-A4 METHOD OF SYNTHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS 1993-07-21 EP disclosed
EP-0524942-A1 METHOD OF SYNTHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS LYNX THERAPEUTICS, INC. (US) 1993-02-03 EP disclosed
US-5151510-A METHOD OF SYNETHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS APPLIED BIOSYSTEMS, INC. (US) 1992-09-29 US disclosed
WO-1991016331-A1 METHOD OF SYNTHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS APPLIED BIOSYSTEMS, INC. (US) 1991-10-31 WO disclosed