Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608737 | 0.87 | DNMT1 (0.38) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL9350829 | 0.86 | DNMT1 (0.39) | ALDH1A1MAPTMPIHSD17B10MEN1 | |
| SCHEMBL160594 | 0.85 | ALDH1A1 (0.37) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL30391805 | 0.85 | ALDH1A1 (0.37) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL31566355 | 0.84 | ALDH1A1 (0.38) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL164194 | 0.84 | ALDH1A1 (0.38) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL8614470 | 0.84 | SALL4 (0.43) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL16811762 | 0.78 | CYP1A2 (0.39) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL17758852 | 0.77 | ALDH1A1 (0.33) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 | |
| SCHEMBL7544297 | 0.77 | ALDH1A1 (0.35) | ALDH1A1CYP2C19MAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |