Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447996 | 1.00 | HTR2A (0.44) | HTR2AHTR2CHTR2BSIGMAR1DRD2 | |
| SCHEMBL14429883 | 0.80 | ALOX15 (0.44) | SIGMAR1PDPK1CYP3A4PRCPMEN1 | |
| SCHEMBL1745011 | 0.80 | ALOX15 (0.44) | SIGMAR1PDPK1CYP3A4PRCPMEN1 | |
| SCHEMBL9493200 | 0.77 | PDPK1 (0.43) | HTR2APDPK1PRCPRET | |
| SCHEMBL28223707 | 0.77 | PDPK1 (0.43) | HTR2AHTR2CHTR2BPDPK1ACP3 | |
| SCHEMBL11251250 | 0.76 | HTR2A (0.43) | HTR2AHTR2CHTR2BSIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL9296485 | 0.74 | HTR2A (0.45) | HTR2AHTR2CHTR2BSIGMAR1DRD2 | |
| SCHEMBL2400566 | 0.74 | PDPK1 (0.41) | HTR2AHTR2CHTR2BPDPK1PRCP | |
| SCHEMBL2583993 | 0.74 | PDPK1 (0.53) | HTR2AHTR2CHTR2BPDPK1PRCP | |
| SCHEMBL2817474 | 0.73 | HTR2C (0.55) | HTR2AHTR2CHTR2BSIGMAR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262250-A | Synthetic method of aromatic ring benzyl ortho-position dialkyl | 乐威医药（江苏）股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-3661601-A1 | METHODS FOR INCREASING FERTILITY | Newsouth Innovations Pty Limited (AU) | 2020-06-10 | — | — | EP | disclosed |
| CN-106137862-B | Composition and cosmetics containing nano Chinese angelica | 南京谷润生物科技有限公司 | 2019-03-08 | — | — | CN | disclosed |
| WO-2019023748-A1 | METHODS FOR INCREASING FERTILITY | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2019-02-07 | — | — | WO | disclosed |
| CN-106137862-A | Composition containing nano Chinese angelica and cosmetics | 南京谷润生物科技有限公司 | 2016-11-23 | — | — | CN | disclosed |
| EP-3068364-A1 | SENESCENCE AND SENESCENCE ASSOCIATED SECRETORY PHENOTYPE | NewSouth Innovations Pty Limited (AU) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015070280-A1 | SENESCENCE AND SENESCENCE ASSOCIATED SECRETORY PHENOTYPE | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2015-05-21 | — | — | WO | disclosed |
| US-5756790-A | FROM KETONES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |