Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911390 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL9612075 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL861077 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL860991 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL861154 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL9612028 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL9612019 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL9911388 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL861071 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL9911392 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432468-A2 | METHODS OF MODULATING URIC ACID LEVELS | Ardea Biosciences, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135536-A2 | METHODS OF MODULATING URIC ACID LEVELS | ARDEA BIOSCIENCES, INC. (US) | 2010-11-25 | — | — | WO | disclosed |