Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 11/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | CCKAR | P32238 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468540 | 1.00 | CCKBR (0.82) | CCKBRKCNH2CCKARCYP3A4MAPT | |
| SCHEMBL8681438 | 1.00 | CCKBR (0.82) | CCKBRKCNH2CCKARCYP3A4MAPT | |
| SCHEMBL641958 | 0.90 | CCKBR (1.00) | CCKBRKCNH2CCKARCYP3A4MAPT | |
| SCHEMBL8682548 | 0.88 | CCKBR (0.64) | CCKBRKCNH2CCKAR | |
| SCHEMBL9865815 | 0.87 | CCKBR (0.65) | CCKBRKCNH2 | |
| SCHEMBL9468952 | 0.82 | CCKBR (0.81) | CCKBR | |
| SCHEMBL8681481 | 0.82 | CCKBR (0.81) | CCKBR | |
| SCHEMBL9109762 | 0.82 | CCKBR (0.64) | CCKBRCCKAR | |
| SCHEMBL642143 | 0.82 | CCKBR (0.85) | CCKBRCCKAR | |
| SCHEMBL8681334 | 0.80 | CCKBR (0.63) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730456-A4 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO INC (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0730456-A1 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO. INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014472-A1 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |