Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865628 | 0.82 | APLNR (0.48) | SLC2A1CD274PTPN1 | |
| SCHEMBL14230496 | 0.76 | CD274 (0.53) | CD274KDM4EPOLBPTPN1 | |
| SCHEMBL28915772 | 0.74 | APLNR (0.57) | ERN1SMN1; SMN2KDM4EPTPN1 | |
| SCHEMBL27449774 | 0.74 | PTPN1 (0.56) | ERN1CYP3A4USP2MAPK1SMN1; SMN2 | |
| SCHEMBL5383983 | 0.73 | CDC25C (0.60) | SMN1; SMN2 | |
| SCHEMBL6493357 | 0.72 | CD274 (0.48) | CD274KDM4EPTPN1 | |
| SCHEMBL743276 | 0.71 | ERN1 (0.57) | ERN1CYP3A4USP2MAPK1SMN1; SMN2 | |
| SCHEMBL28155887 | 0.71 | PTPN1 (0.49) | SLC2A1CD274KDM4EPTPN1 | |
| SCHEMBL7115040 | 0.70 | HMGCR (0.50) | ERN1CYP3A4USP2MAPK1SMN1; SMN2 | |
| SCHEMBL19943746 | 0.69 | PTPN1 (0.46) | ERN1CYP3A4USP2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831806-A1 | MULTIDENTATE METAL COMPLEXES AND METHODS OF MAKING AND USING THEREOF | WASHINGTON UNIVERSITY (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040108-A1 | MULTIDENTATE METAL COMPLEXES AND METHODS OF MAKING AND USING THEREOF | WASHINGTON UNIVERSITY (US) | 1996-12-19 | — | — | WO | disclosed |