SCHEMBL8611482

SCHEMBL8611482

CCOC(=O)c1cc(OCN2C(=O)c3c(C(C)C)cc(OC)cc3S2(=O)=O)n(-c2ccccc2)n1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 0.55
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8609841 0.87 ELANE (0.60) ELANE
SCHEMBL8609098 0.84 ELANE (0.60) ELANE
SCHEMBL8616013 0.84 ELANE (0.61) ELANE
SCHEMBL8614058 0.82 ELANE (0.57) ELANE
SCHEMBL8616353 0.82 ELANE (0.63) ELANE
SCHEMBL7303907 0.80 ELANE (0.66) ELANE
SCHEMBL9010433 0.77 ELANE (0.74) ELANE
SCHEMBL8611658 0.76 ELANE (0.53) ELANE
SCHEMBL7402115 0.76 POLB (0.54) POLB
SCHEMBL8611258 0.75 ELANE (0.63) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750550-A RESPIRATORY SYSTEM DISORDERS SANOFI (FR) 1998-05-12 US disclosed