Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | DCAF1 | Q9Y4B6 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011921 | 0.96 | HTR3E (0.41) | MEN1KMT2AACP3DCAF1TRPM8 | |
| Modafinil SCHEMBL5031196 | 0.91 | CYP1A2 (0.39) | DCAF1LMNAMAPK1NPSR1 | |
| SCHEMBL9216087 | 0.87 | CNR2 (0.42) | MEN1KMT2ALMNATSHRNPSR1 | |
| Modafinil SCHEMBL34488 | 0.87 | CYP2D6 (0.44) | LMNAMAPK1NPSR1 | |
| (S)-Modafinil SCHEMBL1403524 | 0.87 | CYP2D6 (0.44) | LMNAMAPK1NPSR1 | |
| Modafinil SCHEMBL3238686 | 0.87 | CYP2D6 (0.44) | LMNAMAPK1NPSR1 | |
| Armodafinil SCHEMBL34489 | 0.87 | CYP2D6 (0.44) | LMNAMAPK1NPSR1 | |
| Modafinil SCHEMBL1560974 | 0.87 | CYP2D6 (0.44) | LMNAMAPK1NPSR1 | |
| Modafinil SCHEMBL193837 | 0.85 | CYP2D6 (0.41) | LMNAMAPK1NPSR1 | |
| Modafinil SCHEMBL3908867 | 0.84 | EPHX1 (0.42) | ALDH1A1LMNAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719168-A | Acetamide derivatives and their use as feeding behaviour modifiers | LABORATOIRE L. LAFON (FR) | 1998-02-17 | — | — | US | claimed |
| EP-0706512-B1 | ACETAMIDE DERIVATIVES AND THEIR USE FOR MODIFYING FEEDING BEHAVIOUR MODIFIERS | LAFON LABOR (FR) | 1998-04-08 | — | — | EP | disclosed |
| US-5719168-A | Acetamide derivatives and their use as feeding behaviour modifiers | LABORATOIRE L. LAFON (FR) | 1998-02-17 | — | — | US | disclosed |
| EP-0706512-A1 | ACETAMIDE DERIVATIVES AND THEIR USE FOR MODIFYING FEEDING BEHAVIOUR MODIFIERS | LABORATOIRE L. LAFON (FR) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001333-A1 | ACETAMIDE DERIVATIVES AND THEIR USE FOR MODIFYING FEEDING BEHAVIOUR MODIFIERS | LABORATOIRE L. LAFON (FR) | 1995-01-12 | — | — | WO | disclosed |