Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616603 | 0.85 | ITGB2 (0.32) | — | |
| SCHEMBL161183 | 0.74 | ABCG2 (0.39) | ABCG2TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL3404505 | 0.72 | ABCG2 (0.37) | ABCG2TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL6904035 | 0.71 | ABCG2 (0.36) | ABCG2TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL83574 | 0.71 | NQO2 (0.40) | ABCG2TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL5907509 | 0.67 | NQO2 (0.37) | ABCG2 | |
| SCHEMBL4060952 | 0.67 | TAAR1 (0.33) | ABCG2TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL63619 | 0.67 | AOC3 (0.35) | ABCG2TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL8925096 | 0.63 | ABCG2 (0.38) | ABCG2 | |
| SCHEMBL8638641 | 0.63 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835242-A1 | THIOAMIDES S-OXIDES FOR USE AS PESTICIDES | Novartis AG (CH) | 1998-04-15 | — | — | EP | disclosed |
| US-5726343-A | REACTION OF A BORONIC ACID COMPOUND WITH A METHOXYIMINOACETIC ESTER, INSECTICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997000859-A1 | THIOAMIDES S-OXIDES FOR USE AS PESTICIDES | NOVARTIS AG (CH) | 1997-01-09 | — | — | WO | disclosed |