Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212957 | 0.83 | ABCG2 (0.40) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL161183 | 0.82 | ABCG2 (0.39) | ALDH1A1TSHRHSD17B10NQO2CYP19A1 | |
| SCHEMBL9738660 | 0.80 | KDM4E (0.41) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9740282 | 0.80 | RIPK3 (0.37) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11571390 | 0.78 | PREP (0.43) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6210971 | 0.76 | PDE4A (0.41) | MAPTALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL6784931 | 0.75 | HSP90AA1 (0.30) | HSP90AA1HSP90AB1 | |
| SCHEMBL83574 | 0.74 | NQO2 (0.40) | ALDH1A1LMNAGAATSHRNQO2 | |
| SCHEMBL15377351 | 0.73 | ALOX5 (0.45) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4807540 | 0.73 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651737-B1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | CIBA GEIGY AG (CH) | 1998-07-29 | — | — | EP | claimed |