Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310648 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL3769590 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL15757962 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL5496297 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL15758099 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL2292977 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL5501007 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL1395981 | 0.92 | — | — | |
| SCHEMBL5499984 | 0.80 | — | — | |
| SCHEMBL1494238 | 0.79 | TSHR (0.35) | TSHRTHRBALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817302-A | POLYSILSESQUISILOXANES, COSMETICS | GENERAL ELECTRIC COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5684112-A | Low viscosity organofunctionalized siloxysilicates and cosmetic formulations therewith | GENERAL ELECTRIC COMPANY (US) | 1997-11-04 | — | — | US | disclosed |