SCHEMBL2292977

SCHEMBL2292977

CCCCCCCC[Si](C)(C)O[SiH3]

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 3/20 0.38
EPHX2 P34913 1/20 0.33
LMNA P02545 3/20 0.32
DNM1 Q05193 6/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15758099 1.00 TSHR (0.40) TSHRTHRBALDH1A1EPHX2LMNA
SCHEMBL3769590 1.00 TSHR (0.40) TSHRTHRBALDH1A1EPHX2LMNA
SCHEMBL15757962 1.00 TSHR (0.40) TSHRTHRBALDH1A1EPHX2LMNA
SCHEMBL5496297 1.00 TSHR (0.40) TSHRTHRBALDH1A1EPHX2LMNA
SCHEMBL5501007 1.00 TSHR (0.40) TSHRTHRBALDH1A1EPHX2LMNA
SCHEMBL9310648 1.00 TSHR (0.40) TSHRTHRBALDH1A1EPHX2LMNA
SCHEMBL8612261 0.97 TSHR (0.35) TSHRTHRBALDH1A1LMNA
SCHEMBL1395981 0.90
SCHEMBL771775 0.79 TSHR (0.44) TSHRTHRBALDH1A1LMNADNM1
SCHEMBL17105915 0.79 TSHR (0.44) TSHRTHRBALDH1A1LMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029057-B2 Single component developer composition XEROX CORPORATION (US) 2015-05-12 US claimed
US-20140315127-A1 Single Component Developer Composition XEROX CORPORATION (US) 2014-10-23 US claimed
US-9029057-B2 Single component developer composition XEROX CORPORATION (US) 2015-05-12 US disclosed
US-9029057-B2 Single component developer composition XEROX CORPORATION (US) 2015-05-12 US disclosed
US-20140315127-A1 Single Component Developer Composition XEROX CORPORATION (US) 2014-10-23 US disclosed
US-20140315127-A1 Single Component Developer Composition XEROX CORPORATION (US) 2014-10-23 US disclosed
US-8304568-B2 Organopolysiloxanes having polyhydroxyamido groups and preparation thereof WACKER CHEMIE AG (DE) 2012-11-06 US disclosed
EP-2176320-B1 ORGANOPOLYSILOXANES HAVING POLYHYDROXYAMIDO GROUPS AND PREPARATION THEREOF WACKER CHEMIE AG (DE) 2011-09-14 EP disclosed
US-20110190525-A1 ORGANOPOLYSILOXANES HAVING POLYHYDROXYAMIDO GROUPS AND PREPARATION THEREOF WACKER CHEMIE AG (DE) 2011-08-04 US disclosed
EP-2176320-A1 ORGANOPOLYSILOXANES HAVING POLYHYDROXYAMIDO GROUPS AND PREPARATION THEREOF Wacker Chemie AG (DE) 2010-04-21 EP disclosed
WO-2009019144-A1 ORGANOPOLYSILOXANES HAVING POLYHYDROXYAMIDO GROUPS AND PREPARATION THEREOF WACKER CHEMIE AG (DE) 2009-02-12 WO disclosed
EP-1361915-A4 POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE WATERS INVESTMENTS LTD (US) 2006-10-04 EP disclosed
WO-2005079427-A2 POROUS HYBRID MONOLITH MATERIALS WITH ORGANIC GROUPS REMOVED FROM THE SURFACE WATERS INVESTMENTS LIMITED (US) 2005-09-01 WO disclosed
EP-1361915-A1 POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE Waters Investments Limited (US) 2003-11-19 EP disclosed
WO-2002060562-A1 POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE WATERS INVESTMENTS LIMITED (US) 2002-08-08 WO disclosed
US-6093782-A MIXTURE COMPRISING AN ORGANOSILICON COMPOUND HAVING VINYL MOIETIES AND AN ORGANOSILICON COMPOUND HAVING SILICON-HYDROGEN MOIETIES, HYDROSILATION CATALYST, ROOM TEMPERATURE CROSSLINKING INHIBITOR; RELEASE AGENTS WACKER-CHEMIE GMBH (DE) 2000-07-25 US disclosed
US-3960810-A ORGANOSILOXANE POLYMER, CATALYST DOW CORNING LIMITED (WA) 1976-06-01 US disclosed