Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611588 | 1.00 | TDP1 (0.37) | TDP1TSHRFDPSALDH1A1LMNA | |
| SCHEMBL8611855 | 1.00 | TDP1 (0.37) | TDP1TSHRFDPSALDH1A1LMNA | |
| SCHEMBL8612393 | 0.90 | TDP1 (0.40) | TDP1TSHRFDPSALDH1A1LMNA | |
| SCHEMBL11240509 | 0.86 | ALDH1A1 (0.41) | TDP1TSHRFDPSALDH1A1TP53 | |
| SCHEMBL18027879 | 0.84 | ALDH1A1 (0.41) | TSHRFDPSALDH1A1TP53 | |
| SCHEMBL7280456 | 0.84 | — | — | |
| SCHEMBL10271079 | 0.82 | ALDH1A1 (0.45) | TSHRFDPSALDH1A1 | |
| SCHEMBL13282955 | 0.81 | TDP1 (0.30) | TDP1 | |
| SCHEMBL24213867 | 0.79 | TDP1 (0.35) | TDP1TSHRALDH1A1TP53 | |
| SCHEMBL240164 | 0.79 | ALDH1A1 (0.37) | TDP1TSHRFDPSALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827855-A | ANTICHOLESTEROL AGENTS TREATING CARDIOVASCULAR DISORDERS; ENZYME INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1998-10-27 | — | — | US | disclosed |
| EP-0605230-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1997-08-27 | — | — | EP | disclosed |
| US-5451688-A | Inhibit biosynthesis of cholesterol | SANKYO COMPANY, LIMITED (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0605230-A1 | Hexanhydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-4969950-A | Triazole compounds and methods for regulating plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0291852-A1 | Triazole compounds, process for their preparation and method for plant growth regulation | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | disclosed |