SCHEMBL8612411

SCHEMBL8612411

O=C(Nc1ccccc1)OO

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.58
TSHR P16473 2/20 0.58
TP53 P04637 1/20 0.58
EPHX1 P07099 1/20 0.58
EPHX2 P34913 1/20 0.58
CDK9 P50750 1/20 0.58
CLK4 Q9HAZ1 1/20 0.58
NAPRT Q6XQN6 1/20 0.54
HSD17B10 Q99714 1/20 0.54
GAA P10253 3/20 0.53
ALDH1A1 P00352 2/20 0.53
HTT P42858 1/20 0.53
RAB9A P51151 5/20 0.52
NPC1 O15118 4/20 0.52
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
MAPT P10636 1/20 0.52
KDM4E B2RXH2 1/20 0.51
BLM P54132 1/20 0.51
HSP90AA1 P07900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2244779 0.83 SMN1; SMN2 (0.61) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL8827353 0.83 SMN1; SMN2 (0.61) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL282531 0.81 SMN1; SMN2 (0.71) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL4315341 0.79 SMN1; SMN2 (0.56) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL28392201 0.79 SMN1; SMN2 (0.56) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL514783 0.79 SMN1; SMN2 (0.56) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL1727069 0.79 SMN1; SMN2 (0.56) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL5564047 0.79 SMN1; SMN2 (0.56) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL8884482 0.79 SMN1; SMN2 (0.69) SMN1; SMN2TSHRTP53EPHX1EPHX2
SCHEMBL27519753 0.79 SMN1; SMN2 (0.56) SMN1; SMN2TSHRTP53EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102105496-A Method of making carbamate functional materials BASF CORP 2011-06-22 CN claimed
CN-107870518-A Anti-corrosion agent composition and patterning method 信越化学工业株式会社 2018-04-03 CN disclosed
CN-102105496-A Method of making carbamate functional materials BASF CORP 2011-06-22 CN disclosed
EP-0726248-B1 Process for the preparation of anilides of O-acyloxycarboxylic acids CLARIANT GMBH (DE) 1998-04-15 EP disclosed
EP-0688763-B1 Process for preparing anilides of hydroxycarboxylic acids CLARIANT GMBH (DE) 1998-04-08 EP disclosed
EP-0753507-A1 Process for the preparation of hydroxycarboxylic acid anilides HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-15 EP disclosed
EP-0726248-A1 Process for the preparation of anilides of O-acyloxycarboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-14 EP disclosed
EP-0688763-A1 Process for preparing anilides of hydroxycarboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP disclosed