Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074710 | 0.89 | ALDH1A1 (0.54) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL28333317 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL2244779 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL9629186 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL8710363 | 0.84 | RAB9A (0.51) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL11321069 | 0.84 | NPC1 (0.62) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL28049157 | 0.83 | RAB9A (0.58) | ALDH1A1RAB9AKMT2ANPC1MAPT | |
| SCHEMBL282531 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL8612411 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL13979800 | 0.82 | ALDH1A1 (0.55) | SMN1; SMN2TSHRTP53EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |