Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018695 | 0.93 | MC4R (0.38) | MC4RKCNH2SLC9A1PLAU | |
| SCHEMBL8609018 | 0.86 | SLC9A1 (0.36) | MC4RKCNH2SOS1SLC9A1PLAU | |
| SCHEMBL8610974 | 0.86 | SOS1 (0.36) | MC4RKCNH2SOS1SLC9A1PLAU | |
| SCHEMBL8613375 | 0.84 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL8609014 | 0.84 | NOTUM (0.43) | KCNH2SOS1SLC9A1 | |
| SCHEMBL8612577 | 0.81 | SLC9A1 (0.37) | MC4RKCNH2SOS1SLC9A1 | |
| SCHEMBL8614188 | 0.81 | MRGPRX4 (0.40) | SLC9A1 | |
| SCHEMBL8608691 | 0.80 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL9018711 | 0.79 | PLAU (0.41) | MC4RKCNH2SLC9A1PLAU | |
| SCHEMBL9018721 | 0.79 | PLAU (0.41) | MC4RKCNH2SLC9A1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |