SCHEMBL8612650

SCHEMBL8612650

COC(C)OC.O=Cc1ccc(CCl)o1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GAA P10253 1/20 0.36
POLB P06746 3/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 3/20 0.35
NPC1 O15118 2/20 0.35
MAPT P10636 2/20 0.35
RAB9A P51151 2/20 0.35
HSP90AA1 P07900 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
STAT1 P42224 1/20 0.33
TP53 P04637 2/20 0.32
HPGD P15428 1/20 0.32
MDM2 Q00987 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8586891 0.84 ALDH1A1 (0.45) ALDH1A1TSHRHTTL3MBTL1GAA
SCHEMBL669513 0.84
Aes-103 SCHEMBL9256544 0.84 ALDH1A1 (0.71) ALDH1A1TSHRHTTL3MBTL1GAA
Acetonitrile SCHEMBL28721540 0.78 ALDH1A1 (0.52) ALDH1A1TSHRHTTL3MBTL1GAA
SCHEMBL6571061 0.75 POLB (0.40) ALDH1A1TSHRHTTL3MBTL1GAA
SCHEMBL29219910 0.74 ALDH1A1 (0.47) ALDH1A1TSHRHTTL3MBTL1GAA
Furfural SCHEMBL29233534 0.72 ALDH1A1 (0.60) ALDH1A1TSHRHTTL3MBTL1GAA
SCHEMBL721921 0.72 ALDH1A1 (0.57) ALDH1A1TSHRHTTL3MBTL1GAA
SCHEMBL16564347 0.72 ALDH1A1 (0.57) ALDH1A1TSHRHTTL3MBTL1GAA
SCHEMBL3058101 0.71 ALDH1A1 (0.52) ALDH1A1TSHRHTTL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10130251-A None JP disclosed
JP-H10130251-A PURIFICATION OF 2-FURALDEHYDE ACETAL DERIVATIVE SUMITOMO CHEM CO LTD 1998-05-19 JP disclosed