Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 2/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537574 | 0.92 | CSNK1A1 (0.47) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL8613633 | 0.89 | CYP2D6 (0.45) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL8537355 | 0.84 | CSNK1A1 (0.43) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL6538599 | 0.81 | TAAR1 (0.54) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL8539114 | 0.81 | MTOR (0.46) | MTORADKNISCHCSNK1A1TYRO3 | |
| Hydrochloric Acid SCHEMBL10338404 | 0.80 | TAAR1 (0.53) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL8537087 | 0.80 | CSNK1A1 (0.45) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL8535623 | 0.80 | CSNK1A1 (0.40) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL8536169 | 0.78 | ALDH1A1 (0.52) | MTORADKNISCHCSNK1A1TYRO3 | |
| SCHEMBL8540419 | 0.78 | CSNK1A1 (0.42) | MTORADKNISCHCSNK1A1TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |