Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018669 | 0.92 | SLC9A1 (0.51) | SLC9A1KCNH2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8611037 | 0.86 | SLC9A1 (0.50) | SLC9A1KCNH2CFTR | |
| SCHEMBL8611003 | 0.85 | NOTUM (0.48) | SLC9A1KCNH2CFTR | |
| SCHEMBL8613937 | 0.84 | SLC9A1 (0.38) | SLC9A1GAA | |
| SCHEMBL8611156 | 0.82 | SLC9A1 (0.47) | SLC9A1KCNH2CFTR | |
| SCHEMBL8612636 | 0.81 | SLC9A1 (0.53) | SLC9A1KCNH2 | |
| SCHEMBL9018703 | 0.80 | SLC9A1 (0.43) | SLC9A1KCNH2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9018663 | 0.76 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL7799903 | 0.76 | SLC9A1 (0.57) | SLC9A1KCNH2 | |
| SCHEMBL9018708 | 0.76 | SLC9A1 (0.57) | SLC9A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |