Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953224 | 0.90 | TDP1 (0.39) | TDP1HCAR2 | |
| SCHEMBL6952411 | 0.90 | TDP1 (0.39) | TDP1HCAR2 | |
| Potassium Ion SCHEMBL8613013 | 0.88 | TDP1 (0.32) | TDP1 | |
| SCHEMBL8613976 | 0.87 | TDP1 (0.43) | TDP1 | |
| SCHEMBL8611146 | 0.83 | AKR1C3 (0.33) | TDP1 | |
| SCHEMBL6958877 | 0.79 | TDP1 (0.45) | TDP1 | |
| Potassium Ion SCHEMBL6959314 | 0.78 | TDP1 (0.30) | TDP1 | |
| SCHEMBL8611550 | 0.75 | TDP1 (0.40) | TDP1HCAR2 | |
| SCHEMBL6954011 | 0.74 | HRH4 (0.40) | — | |
| SCHEMBL6950349 | 0.74 | HRH4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719280-A | REACTING AMINE SUBSTITUTED BENZOCYCLOALKANE WITH DIALKYLOXYACETALDEHYDE IN PRESENCE OF REDUCING AGENT OR CATALYTIC HYDROGENATION, TREATING WITH THIOCYANIC ACID | SYNTEX (U.S.A.) INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0757677-A1 | BENZOCYCLOALKYLAZOLETHIONE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5538988-A | CARDIOVASCULAR DISORDERS AND DOPAMINE HYDROLASE ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. | 1996-07-23 | — | — | US | disclosed |
| WO-1995029165-A2 | BENZOCYCLOALKYLAZ0LETHIONE DERIVATIVES AS DOPAMIN BETA-HYDROXYLASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1995-11-02 | — | — | WO | disclosed |