Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 20/20 | 0.76 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.73 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616254 | 0.86 | SRD5A2 (1.00) | SRD5A2HSD3B1SRD5A1 | |
| SCHEMBL8616250 | 0.86 | SRD5A2 (1.00) | SRD5A2HSD3B1SRD5A1 | |
| SCHEMBL8611352 | 0.85 | SRD5A2 (1.00) | SRD5A2HSD3B1SRD5A1 | |
| SCHEMBL8610454 | 0.84 | SRD5A2 (1.00) | SRD5A2HSD3B1SRD5A1 | |
| SCHEMBL8610451 | 0.84 | SRD5A2 (1.00) | SRD5A2HSD3B1SRD5A1 | |
| SCHEMBL12651156 | 0.82 | SRD5A2 (0.80) | SRD5A2 | |
| SCHEMBL9159638 | 0.82 | SRD5A2 (0.80) | SRD5A2 | |
| SCHEMBL12606608 | 0.82 | SRD5A2 (0.80) | SRD5A2 | |
| SCHEMBL19544537 | 0.82 | SRD5A2 (0.80) | SRD5A2HSD3B1SRD5A1 | |
| SCHEMBL19544512 | 0.81 | SRD5A2 (0.79) | SRD5A2HSD3B1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641356-B1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO WELLCOME INC (US) | 1998-04-22 | — | — | EP | claimed |
| WO-1993013124-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO INC. (US) | 1993-07-08 | — | — | WO | claimed |
| EP-0641356-B1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO WELLCOME INC (US) | 1998-04-22 | — | — | EP | disclosed |
| US-5543406-A | TREATING ANDROGEN RESPONSIVE OR MEDIATED DISEASE | GLAXO WELLCOME, INC. (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0641356-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO WELLCOME INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993013124-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO INC. (US) | 1993-07-08 | — | — | WO | disclosed |