Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651156 | 1.00 | SRD5A2 (0.80) | SRD5A2 | |
| SCHEMBL9159638 | 1.00 | SRD5A2 (0.80) | SRD5A2 | |
| SCHEMBL19544537 | 0.91 | SRD5A2 (0.80) | SRD5A2 | |
| SCHEMBL19544512 | 0.90 | SRD5A2 (0.79) | SRD5A2 | |
| SCHEMBL8616254 | 0.89 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL8616250 | 0.89 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL8611619 | 0.86 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL8611622 | 0.86 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL8528588 | 0.86 | SRD5A2 (0.76) | SRD5A2 | |
| SCHEMBL8532138 | 0.86 | SRD5A2 (1.00) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481530-B2 | 3β-hydroxysteroid dehydrogenase inhibitors | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481530-B2 | 3β-hydroxysteroid dehydrogenase inhibitors | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2013-07-09 | — | — | US | disclosed |
| US-20110124639-A1 | 3 BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124639-A1 | 3 BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | HSD17B3, HSD3B1, HSD17B1 | SRD5A2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.