Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613864 | 0.85 | MEN1 (0.46) | MAOBTOP1ALOX5MAOAMAPT | |
| SCHEMBL8619233 | 0.85 | MAOB (0.44) | MAOBTOP1ALOX5MAOAMAPT | |
| SCHEMBL8617581 | 0.84 | MAOB (0.50) | MAOBTOP1ALOX5MAOAMAPT | |
| SCHEMBL8613086 | 0.84 | MAOB (0.59) | MAOBTOP1ALOX5MAOAPARP15 | |
| SCHEMBL8616016 | 0.81 | GSTP1 (0.54) | MAOBTOP1ALOX5MAOAMAPT | |
| SCHEMBL8613938 | 0.80 | GSTP1 (0.52) | MAOBTOP1ALOX5MAOAMAPT | |
| SCHEMBL8615452 | 0.80 | MAOB (0.55) | MAOBTOP1ALOX5MAOAPARP15 | |
| SCHEMBL8613447 | 0.80 | MAOB (0.55) | MAOBTOP1ALOX5MAOAMAPT | |
| SCHEMBL8614719 | 0.80 | FEN1 (0.49) | MAOBTOP1ALOX5MAOAMAPT | |
| SCHEMBL8618126 | 0.79 | MAOB (0.47) | MAOBTOP1ALOX5MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0665836-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |