SCHEMBL8613161

SCHEMBL8613161

CON=C(C(=O)OC)c1ccccc1C(=O)Cl

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.50
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
CTSD P07339 1/20 0.37
CFTR P13569 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PKM P14618 1/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
ATM Q13315 1/20 0.35
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8617535 0.85 HIF1A (0.52) HIF1AALDH1A1ALOX15HSD17B10KDM4E
SCHEMBL29445316 0.81 HIF1A (0.51) HIF1ALMNAPOLB
SCHEMBL29883529 0.81 HIF1A (0.51) HIF1ALMNAPOLB
SCHEMBL3747106 0.81 HIF1A (0.51) HIF1ALMNAPOLB
SCHEMBL6155893 0.81 HIF1A (0.51) HIF1ALMNAPOLB
SCHEMBL6705432 0.81 LMNA (0.55) HIF1AALDH1A1ALOX15LMNATSHR
SCHEMBL7040691 0.81 HIF1A (0.51) HIF1ALMNAPOLB
SCHEMBL6705433 0.81 LMNA (0.55) HIF1AALDH1A1ALOX15LMNATSHR
SCHEMBL29810082 0.81 HIF1A (0.51) HIF1ALMNAPOLB
SCHEMBL7119395 0.81 LMNA (0.55) HIF1AALDH1A1ALOX15LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5719171-A INSECTICIDES; MITICIDES; NEMATOCIDES; FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-02-17 US disclosed
US-5594020-A FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
EP-0621277-A2 Diarylderivatives and their use for the protection of plants BASF Aktiengesellschaft (DE) 1994-10-26 EP disclosed