Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.67 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.67 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.67 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.67 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.67 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480413 | 0.90 | GRIA1 (0.60) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8191679 | 0.85 | GRIK1 (0.73) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8610630 | 0.84 | GRIK1 (0.53) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8128429 | 0.83 | CA12 (0.46) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7487740 | 0.82 | CA12 (0.50) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8609560 | 0.81 | GRIK1 (0.69) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8612182 | 0.81 | GRIA1 (0.69) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL30661076 | 0.80 | GRIK1 (0.65) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8190512 | 0.80 | GRIK1 (0.65) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8196324 | 0.78 | GRIK1 (0.63) | GRIK1GRIK2GRIK3GRIK4GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |