Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 14/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610247 | 0.93 | TYMP (0.57) | TYMPADORA1DNMT3B | |
| SCHEMBL8610677 | 0.91 | TYMP (0.68) | TYMPADORA1DNMT3B | |
| SCHEMBL8610717 | 0.89 | TYMP (0.48) | TYMPADORA1DNMT3B | |
| SCHEMBL8610715 | 0.89 | TYMP (0.48) | TYMPADORA1DNMT3B | |
| SCHEMBL8614561 | 0.85 | TYMP (0.51) | TYMPADORA1 | |
| SCHEMBL8609070 | 0.85 | TYMP (0.51) | TYMPADORA1 | |
| SCHEMBL8610332 | 0.83 | TYMP (0.67) | TYMPADORA1 | |
| SCHEMBL8610982 | 0.83 | TYMP (0.83) | TYMPADORA1 | |
| SCHEMBL8611790 | 0.81 | TYMP (0.64) | TYMPADORA1 | |
| SCHEMBL8611071 | 0.81 | TYMP (0.49) | TYMPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5525720-A | Synthesis of 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosyl purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |