Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TACR3 | P29371 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615494 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2TP53KDM4ELMNATACR3 | |
| SCHEMBL8613990 | 0.91 | TACR3 (0.39) | KDM4ETACR3MAPTALDH1A1HPGD | |
| SCHEMBL8615573 | 0.90 | TACR3 (0.37) | SMN1; SMN2KDM4ETACR3MAPTALDH1A1 | |
| SCHEMBL8615853 | 0.90 | TACR3 (0.37) | SMN1; SMN2TP53KDM4ETACR3MAPT | |
| SCHEMBL8617680 | 0.89 | TACR3 (0.35) | SMN1; SMN2TP53KDM4ELMNATACR3 | |
| SCHEMBL8615222 | 0.89 | TACR3 (0.35) | SMN1; SMN2KDM4ELMNATACR3MAPT | |
| SCHEMBL8619346 | 0.89 | TACR3 (0.46) | SMN1; SMN2TP53KDM4ETACR3MAPT | |
| SCHEMBL8616577 | 0.88 | NQO2 (0.36) | SMN1; SMN2TP53KDM4ELMNATACR3 | |
| SCHEMBL8614011 | 0.87 | TACR3 (0.51) | SMN1; SMN2TP53KDM4ELMNATACR3 | |
| SCHEMBL8615511 | 0.87 | TACR3 (0.35) | KDM4ETACR3ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |