Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PDE2A | O00408 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | CD99 | P14209 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613458 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL23780562 | 0.90 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8614480 | 0.90 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL23780561 | 0.90 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8614477 | 0.90 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8613394 | 0.86 | ADORA2A (0.67) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL8613408 | 0.86 | ADORA2A (0.67) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL8614745 | 0.86 | SLC29A1 (0.51) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL8614735 | 0.86 | SLC29A1 (0.51) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL8610576 | 0.84 | ADORA2A (0.64) | ADORA2AADORA3ADORA1CYP1A2ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |