Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | CD99 | P14209 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614745 | 1.00 | SLC29A1 (0.51) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL8610836 | 0.86 | KDM4E (0.53) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL8610847 | 0.86 | KDM4E (0.53) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL8613445 | 0.86 | ADORA2A (0.64) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL8613458 | 0.86 | ADORA2A (0.64) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL23780562 | 0.85 | SLC29A1 (0.58) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL8614477 | 0.85 | SLC29A1 (0.58) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL8614480 | 0.85 | SLC29A1 (0.58) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL23780561 | 0.85 | SLC29A1 (0.58) | SLC29A1CD99ADORA2AADORA3ADORA1 | |
| SCHEMBL8613540 | 0.83 | KDM4E (0.50) | SLC29A1CD99ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |