Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.52 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073874 | 1.00 | ANPEP (0.63) | ANPEPKMT2AMEN1TSHRMMP8 | |
| Hydrochloric Acid SCHEMBL8617103 | 0.98 | ANPEP (0.61) | ANPEPKMT2AMEN1TSHRMMP8 | |
| SCHEMBL10960492 | 0.87 | KDM4E (0.55) | ANPEPMMP8 | |
| Hydrochloric Acid SCHEMBL11142777 | 0.85 | HDAC8 (0.56) | ANPEPMMP8 | |
| SCHEMBL8895419 | 0.85 | AAK1 (0.56) | ANPEPMMP8LARS1 | |
| SCHEMBL24322367 | 0.84 | POLB (0.54) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL22522245 | 0.84 | KMT2A (0.59) | ANPEPKMT2AMEN1MMP8LARS1 | |
| SCHEMBL1792751 | 0.84 | KMT2A (0.59) | ANPEPKMT2AMEN1MMP8LARS1 | |
| SCHEMBL11710494 | 0.84 | POLB (0.54) | KMT2ACYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL4743866 | 0.84 | KMT2A (0.59) | ANPEPKMT2AMEN1MMP8LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0126974-B1 | CARBOXYALKYL PEPTIDE DERIVATIVES | G.D. Searle & Co. (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4568666-A | COLLAGENASE INHIBITORS, ANTIARTJRITIC AGENTS | G. D. SEARLE & CO. (US) | 1986-02-04 | — | — | US | disclosed |
| US-4511504-A | COLLAGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0126974-A1 | Carboxyalkyl peptide derivatives | G.D. Searle & Co. (US) | 1984-12-05 | — | — | EP | disclosed |