Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | MMP8 | P22894 | 5/20 | 0.57 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.51 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792751 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1MAPTANPEP | |
| SCHEMBL22522245 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1MAPTANPEP | |
| Hydrochloric Acid SCHEMBL10520633 | 0.98 | KMT2A (0.58) | KMT2AALDH1A1MEN1MAPTANPEP | |
| Acetic Acid SCHEMBL11135238 | 0.97 | ALDH1A1 (0.56) | KMT2AALDH1A1MEN1MAPTANPEP | |
| SCHEMBL7371699 | 0.90 | ALDH1A1 (0.52) | KMT2AALDH1A1MEN1MAPTANPEP | |
| SCHEMBL15623810 | 0.89 | ERAP2 (0.53) | ANPEPMMP8LARS1 | |
| SCHEMBL22522208 | 0.86 | ANPEP (0.58) | KMT2AALDH1A1MEN1ANPEP | |
| SCHEMBL18274706 | 0.85 | SLC1A1 (0.61) | KMT2AALDH1A1MEN1MAPTMMP8 | |
| SCHEMBL10688879 | 0.84 | ANPEP (0.59) | KMT2AMEN1ANPEPL3MBTL1 | |
| SCHEMBL8613610 | 0.84 | ANPEP (0.63) | KMT2AMEN1ANPEPMMP8LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605540-A | Methods of using MEK inhibitors | EXELIXIS INC (US) | 2009-12-16 | — | — | CN | claimed |
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |