Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268430 | 0.86 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL30589890 | 0.86 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| Ethylene SCHEMBL8565034 | 0.85 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7994441 | 0.85 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL15495109 | 0.85 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL22143546 | 0.85 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3925808 | 0.83 | TSHR (0.62) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6840513 | 0.83 | TSHR (0.62) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2612017 | 0.83 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| Propene SCHEMBL16859720 | 0.83 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667339-B1 | Novel unsaturated peroxides, polymeric peroxides derived therefrom and their uses | ATOCHEM NORTH AMERICA ELF (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5494988-A | FREE RADICAL INITIATORS AS MONOMERS; CROSSLINKING UNSATURATED POLYESTERS; ADDITION, GRAFT AND BLOCK POLYMERIZATION; COMPATIBILIZING BLENDS | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5489699-A | USED AS FREE RADICAL GENERATOR, POLYMERIZING ETHYNICALLY UNSATURATED MONOMERS, CURING AGENT, RHEOLOGICAL MODIFIER,AND FOR GRAFTING AND COMPATIBILIZING POLYMER BLEND | ELFATOCHEM NORTH AMERICA, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5475072-A | Curing; crosslinking; modifiying; grafting; compatibilizing | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-12-12 | — | — | US | disclosed |
| EP-0667339-A1 | Novel unsaturated peroxides, polymeric derived therefrom and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-08-16 | — | — | EP | disclosed |