Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 14/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614133 | 0.91 | TYMP (0.64) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL8611790 | 0.91 | TYMP (0.64) | TYMPADORA1SLC29A1 | |
| SCHEMBL18044398 | 0.89 | TYMP (0.80) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL29822417 | 0.89 | TYMP (0.80) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL31484253 | 0.89 | ADORA1 (0.82) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL8610903 | 0.89 | ADORA1 (0.82) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL8610899 | 0.89 | ADORA1 (0.82) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL1796310 | 0.87 | TYMP (1.00) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL22458597 | 0.87 | TYMP (1.00) | TYMPADORA1SLC29A1DNPH1 | |
| SCHEMBL5270000 | 0.87 | TYMP (1.00) | TYMPADORA1SLC29A1DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5525720-A | Synthesis of 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosyl purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |