Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612197 | 0.84 | CYP1A2 (0.34) | CA1CA9PTGS1PTGS2CYP1A2 | |
| SCHEMBL8610857 | 0.81 | PTGS1 (0.40) | CA1CA9PTGS1PTGS2CYP1A2 | |
| SCHEMBL31314432 | 0.77 | ALOX5 (0.41) | CA1CA9PTGS1PTGS2CYP1A2 | |
| SCHEMBL1567962 | 0.77 | ALOX5 (0.41) | CA1CA9PTGS1PTGS2CYP1A2 | |
| SCHEMBL13309507 | 0.77 | ALOX5 (0.41) | CA1CA9PTGS1PTGS2CYP1A2 | |
| SCHEMBL11750965 | 0.77 | ALOX5 (0.41) | CA1CA9PTGS1PTGS2CYP1A2 | |
| Hydrochloric Acid SCHEMBL30892599 | 0.76 | ALOX5 (0.40) | CA1CA9PTGS1PTGS2CYP1A2 | |
| SCHEMBL10458358 | 0.74 | CA1 (0.67) | CA1CA9CYP1A2TSHR | |
| SCHEMBL12713304 | 0.74 | CYP3A4 (0.42) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL7155377 | 0.71 | CA1 (0.59) | CA1CA9CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718295-B1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN SPA (IT) | 1998-04-22 | — | — | EP | claimed |
| US-5608084-A | AND VASCULAR PATHOLOGIES; MULTISTEP PREPARATION BY REACTING A HYDROQUINONE WITH ALKYL VINYL KETONE, ESTERIFYING HYDROXY 3,4-DIHYDRO-2H-1-BENZOPYRAN, DEMETHYLATING ETHER, REACTING WITH ALKYL 5-BROMOPENTANOATE, HYDROLYZING, TWO MORE STEPS | ALFA WASSERMANN S.P.A. (IT) | 1997-03-04 | — | — | US | claimed |
| EP-0718295-A1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN S.p.A. (IT) | 1996-06-26 | — | — | EP | claimed |
| EP-0718295-B1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN SPA (IT) | 1998-04-22 | — | — | EP | disclosed |
| EP-0718295-A1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN S.p.A. (IT) | 1996-06-26 | — | — | EP | disclosed |