Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 6/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617753 | 0.92 | ACP1 (0.51) | ACP1ABCG2LMNAKDM4EKMT2A | |
| SCHEMBL8620932 | 0.89 | POLB (0.51) | ACP1ABCG2KDM4EKMT2AMEN1 | |
| SCHEMBL8615255 | 0.89 | ABCG2 (0.53) | ACP1ABCG2ABCB1ABCC1 | |
| SCHEMBL8615496 | 0.88 | DHODH (0.50) | ACP1ABCG2KMT2AMEN1ABCB1 | |
| SCHEMBL8615355 | 0.88 | PDE10A (0.55) | ACP1ABCG2KDM4EKMT2AMEN1 | |
| SCHEMBL8615248 | 0.88 | ACP1 (0.44) | ACP1ABCG2KDM4EKMT2AABCB1 | |
| SCHEMBL8619784 | 0.88 | ACP1 (0.44) | ACP1ABCG2KDM4EKMT2AMEN1 | |
| SCHEMBL8617549 | 0.88 | ACP1 (0.49) | ACP1ABCG2LMNAKDM4EKMT2A | |
| SCHEMBL8618214 | 0.88 | ACP1 (0.53) | ACP1ABCG2ABCB1ABCC1PDE10A | |
| SCHEMBL8615808 | 0.85 | KDM4E (0.50) | ACP1ABCG2KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |