Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.55 |
| ▸ | ACP1 | P24666 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617753 | 0.92 | ACP1 (0.51) | PDE10AACP1CYP3A4KDM4EKMT2A | |
| SCHEMBL8618939 | 0.91 | ACP1 (0.44) | PDE10AACP1CYP3A4KDM4EKMT2A | |
| SCHEMBL8617739 | 0.90 | ALDH1A1 (0.47) | PDE10AACP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8620932 | 0.89 | POLB (0.51) | PDE10AACP1KDM4EKMT2AMEN1 | |
| SCHEMBL8618948 | 0.89 | MEN1 (0.50) | PDE10AACP1CYP3A4KDM4EKMT2A | |
| SCHEMBL8618150 | 0.89 | KDM4E (0.48) | PDE10AACP1KDM4EKMT2AMEN1 | |
| SCHEMBL8614008 | 0.88 | ACP1 (0.50) | PDE10AACP1KDM4EKMT2AMEN1 | |
| SCHEMBL8615248 | 0.88 | ACP1 (0.44) | PDE10AACP1KDM4EKMT2AABCB1 | |
| SCHEMBL8619784 | 0.88 | ACP1 (0.44) | PDE10AACP1KDM4EKMT2AMEN1 | |
| SCHEMBL8617549 | 0.88 | ACP1 (0.49) | PDE10AACP1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |