Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617629 | 1.00 | KDM1A (0.49) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8616573 | 0.93 | KDM1A (0.46) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8614212 | 0.89 | FEN1 (0.43) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30080427 | 0.83 | MAPT (0.58) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9706382 | 0.83 | MAPT (0.58) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15129422 | 0.83 | KDM1A (0.60) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29562824 | 0.83 | KDM1A (0.43) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28715221 | 0.83 | KDM1A (0.43) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8616588 | 0.83 | ERN1 (0.47) | KDM1AMRGPRX4PTGER1S1PR5 | |
| SCHEMBL8613438 | 0.81 | KDM1A (0.43) | KDM1AHTR1ASLC6A4MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |