Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612495 | 0.92 | FEN1 (0.47) | ERN1CTSAMRGPRX4KDM1AS1PR5 | |
| SCHEMBL8612994 | 0.91 | ERN1 (0.48) | ERN1CTSAMRGPRX4KDM1AS1PR5 | |
| SCHEMBL8619306 | 0.91 | ERN1 (0.47) | ERN1CTSAMRGPRX4KDM1AS1PR5 | |
| SCHEMBL8614212 | 0.90 | FEN1 (0.43) | ERN1MRGPRX4KDM1AFEN1FFAR1 | |
| SCHEMBL8612830 | 0.87 | GSTP1 (0.50) | FFAR1 | |
| SCHEMBL8617918 | 0.85 | ERN1 (0.46) | ERN1CTSAMRGPRX4KDM1AS1PR5 | |
| SCHEMBL8617629 | 0.83 | KDM1A (0.49) | MRGPRX4KDM1AS1PR5PTGER1 | |
| SCHEMBL8614099 | 0.83 | KDM1A (0.49) | MRGPRX4KDM1AS1PR5PTGER1 | |
| SCHEMBL8617314 | 0.83 | FFAR1 (0.49) | FEN1FFAR1PPARD | |
| SCHEMBL8612822 | 0.83 | ERN1 (0.48) | ERN1CTSAKDM1AS1PR5PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0665836-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |