Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616560 | 0.89 | ERN1 (0.49) | ERN1CTSAPRMT5S1PR5FEN1 | |
| SCHEMBL8615551 | 0.86 | ERN1 (0.49) | ERN1CTSAPRMT5S1PR5FEN1 | |
| SCHEMBL8619252 | 0.85 | ERN1 (0.53) | ERN1CTSAS1PR5KDM1APTGER1 | |
| SCHEMBL8617145 | 0.85 | ERN1 (0.53) | ERN1CTSAS1PR5KDM1APTGER1 | |
| SCHEMBL27756247 | 0.85 | ERN1 (0.51) | ERN1CTSAPRMT5S1PR5FEN1 | |
| SCHEMBL24363273 | 0.84 | ERN1 (0.50) | ERN1CTSAPRMT5S1PR5FEN1 | |
| SCHEMBL8612887 | 0.84 | ERN1 (0.52) | ERN1CTSAPRMT5S1PR5KDM1A | |
| SCHEMBL8611236 | 0.83 | ERN1 (0.51) | ERN1CTSAPRMT5S1PR5KDM1A | |
| SCHEMBL8613062 | 0.82 | ERN1 (0.48) | ERN1CTSAPRMT5S1PR5FEN1 | |
| SCHEMBL8611753 | 0.82 | XDH (0.49) | ERN1CTSAPRMT5S1PR5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |