Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.47 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5393762 | 0.89 | HTR1A (0.56) | KMT5BKMT5CHTR1AADRA1DADRA1A | |
| SCHEMBL30307410 | 0.82 | KMT5B (0.62) | KMT5BKMT5CHTR1AADRA1DADRA1A | |
| SCHEMBL12634152 | 0.79 | KMT5B (0.49) | KMT5BKMT5CHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL23360249 | 0.78 | KMT5B (0.48) | KMT5BKMT5CHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL29862886 | 0.78 | KMT5B (0.48) | KMT5BKMT5CHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL1880318 | 0.78 | KMT5B (0.48) | KMT5BKMT5CHTR1AADRA1DADRA1A | |
| SCHEMBL6861746 | 0.78 | KMT5B (0.78) | KMT5BKMT5CNSD2FERMT2CYP2D6 | |
| SCHEMBL6861753 | 0.78 | KMT5B (0.78) | KMT5BKMT5CNSD2FERMT2CYP2D6 | |
| SCHEMBL14980327 | 0.77 | DYRK1A (0.59) | KMT5BKMT5CHTR1AADRA1DADRA1A | |
| SCHEMBL7510331 | 0.75 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821244-A | CROP PROTECTANTS, PRESERVATIVES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-10-13 | — | — | US | disclosed |
| EP-0701552-A1 | CONDENSED NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS, FUNGICIDES AND ANTIMYCOTICS | Hoechst Schering AgrEvo GmbH (DE) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994021613-A1 | CONDENSED NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS, FUNGICIDES AND ANTIMYCOTICS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-09-29 | — | — | WO | disclosed |