Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614926 | 0.93 | C5AR1 (0.54) | C5AR1PTGER2MRGPRX4PTGER1LMNA | |
| SCHEMBL8612828 | 0.92 | C5AR1 (0.53) | C5AR1PTGER2MRGPRX4PTGER1LMNA | |
| SCHEMBL8611932 | 0.90 | C5AR1 (0.49) | C5AR1GPR34PTGER2MRGPRX4PTGER1 | |
| SCHEMBL8616159 | 0.84 | GSTP1 (0.56) | GPR34GSTP1FFAR1 | |
| SCHEMBL12717052 | 0.84 | MRGPRX4 (0.43) | MRGPRX4PTGER1GSTP1FFAR1RXRA | |
| SCHEMBL8932603 | 0.83 | TAAR1 (0.45) | TAAR1PTGER2ESR2L3MBTL1 | |
| SCHEMBL8613876 | 0.83 | ERN1 (0.51) | C5AR1GPR34TAAR1ESR2MRGPRX4 | |
| SCHEMBL8616654 | 0.82 | USP28 (0.43) | PTGER1GSTP1LMNALRRK2RXRA | |
| SCHEMBL8616573 | 0.82 | KDM1A (0.46) | PTGER2MRGPRX4PTGER1GSTP1L3MBTL1 | |
| SCHEMBL8613340 | 0.82 | ERN1 (0.41) | MRGPRX4PTGER1GSTP1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |