Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 12/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612951 | 0.89 | TYMP (0.71) | TYMPADORA1NT5ESLC29A1PDE2A | |
| SCHEMBL8612956 | 0.89 | TYMP (0.71) | TYMPADORA1NT5ESLC29A1PDE2A | |
| SCHEMBL8612807 | 0.89 | TYMP (0.58) | TYMPADORA1NT5ESLC29A1LMNA | |
| SCHEMBL8610263 | 0.88 | TYMP (0.54) | TYMPADORA1NT5ESLC29A1 | |
| SCHEMBL8610240 | 0.88 | TYMP (0.54) | TYMPADORA1NT5ESLC29A1PDE2A | |
| SCHEMBL8613331 | 0.88 | TYMP (0.46) | TYMPADORA1NT5EPDE2A | |
| SCHEMBL8610234 | 0.88 | TYMP (0.54) | TYMPADORA1NT5ESLC29A1PDE2A | |
| SCHEMBL8610259 | 0.88 | TYMP (0.54) | TYMPADORA1NT5ESLC29A1 | |
| SCHEMBL8613385 | 0.87 | TYMP (0.46) | TYMPADORA1NT5ESLC29A1PDE2A | |
| SCHEMBL8612735 | 0.87 | TYMP (0.54) | TYMPADORA1NT5ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |