⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437614 | 0.81 | — | — | |
| SCHEMBL1129014 | 0.79 | — | — | |
| SCHEMBL11478203 | 0.78 | — | — | |
| SCHEMBL11750156 | 0.77 | KDM4E (0.33) | — | |
| SCHEMBL7106608 | 0.76 | — | — | |
| SCHEMBL2596546 | 0.68 | ALDH1A1 (0.41) | — | |
| SCHEMBL14607263 | 0.68 | LSS (0.31) | — | |
| SCHEMBL21160904 | 0.68 | — | — | |
| SCHEMBL10335366 | 0.68 | — | — | |
| SCHEMBL22753318 | 0.67 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770701-A | Process for preparing targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | claimed |
| US-5770701-A | Process for preparing targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5770710-A | REACTING METHYLTRITHIO ANTIBIOTIC LL-E32288 DERIVATIVE WITH MERCAPTAN COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5606040-A | DERIVATIZED OLIGOSACCHARIDE ANTIBIOTICS WITH CHROMOPHORE | AMERICAN CYANAMID COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0289619-B1 | PROCESS FOR SYNTHESIZING OLIGONUCLEOTIDES AND COMPOUNDS FOR FORMING HIGH-MOLECULAR PROTECTIVE GROUP | DAICEL CHEM (JP) | 1995-08-16 | — | — | EP | disclosed |
| US-5053394-A | Protein-drug reaction product | AMERICAN CYANAMID COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0392384-A2 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| US-4950745-A | Process for synthesis of oligonucleotides and compound for forming polymeric protecting group | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0289619-A1 | PROCESS FOR SYNTHESIZING OLIGONUCLEOTIDES AND COMPOUNDS FOR FORMING HIGH-MOLECULAR PROTECTIVE GROUP | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |