Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | ACP1 | P24666 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615676 | 0.92 | ACP1 (0.48) | ABCB1ABCG2ACP1TACR3CYP3A4 | |
| SCHEMBL8620711 | 0.89 | ACP1 (0.60) | ACP1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8614315 | 0.89 | KMT2A (0.49) | ABCB1ABCG2ACP1MEN1KMT2A | |
| SCHEMBL8617119 | 0.89 | ABCB1 (0.45) | ABCB1ABCG2ACP1MEN1KMT2A | |
| SCHEMBL8616497 | 0.88 | TACR3 (0.61) | ABCB1ABCG2ACP1MEN1KMT2A | |
| SCHEMBL8620945 | 0.87 | NQO2 (0.56) | ABCB1ABCG2ACP1MEN1KMT2A | |
| SCHEMBL8617796 | 0.87 | ACP1 (0.51) | ABCB1ABCG2ACP1MEN1KMT2A | |
| SCHEMBL8617753 | 0.87 | ACP1 (0.51) | ABCB1ABCG2ACP1MEN1KMT2A | |
| SCHEMBL8614778 | 0.86 | ACP1 (0.43) | ABCB1ABCG2ACP1MEN1KMT2A | |
| SCHEMBL8618948 | 0.86 | MEN1 (0.50) | ABCB1ABCG2ACP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |