Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL4303048 | 1.00 | TSHR (0.57) | — | |
| Lithium Ion SCHEMBL906568 | 1.00 | TSHR (0.57) | — | |
| Lithium Ion SCHEMBL29728814 | 0.96 | — | — | |
| SCHEMBL30678822 | 0.93 | TSHR (0.57) | — | |
| SCHEMBL30369243 | 0.93 | TSHR (0.57) | — | |
| SCHEMBL30122785 | 0.93 | TSHR (0.57) | — | |
| SCHEMBL29669897 | 0.93 | TSHR (0.57) | — | |
| SCHEMBL8879449 | 0.93 | TSHR (0.57) | — | |
| SCHEMBL30370471 | 0.93 | TSHR (0.57) | — | |
| Zinc Ion SCHEMBL868059 | 0.93 | TSHR (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525880-B1 | Catalytic alkylation process | FMC CORP (US) | 1998-05-06 | — | — | EP | claimed |
| US-5332853-A | Alkylating tetrachlorosilane or an alkylchlorosilane with an alkyllithium using ether, metal alkoxide, amine, or metal amide as catalyst | FMC CORPORATION (US) | 1994-07-26 | — | — | US | claimed |
| EP-0525880-A1 | Catalytic alkylation process | FMC CORPORATION (US) | 1993-02-03 | — | — | EP | claimed |
| EP-0525880-B1 | Catalytic alkylation process | FMC CORP (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5332853-A | Alkylating tetrachlorosilane or an alkylchlorosilane with an alkyllithium using ether, metal alkoxide, amine, or metal amide as catalyst | FMC CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0525880-A1 | Catalytic alkylation process | FMC CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |