SCHEMBL8615030

SCHEMBL8615030

CCOC(=O)c1ccc2c(c1)OC(O)CC2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 0.47
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
DRD2 P14416 1/20 0.43
PTGER4 P35408 1/20 0.43
MAPT P10636 3/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RAB9A P51151 3/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
ALDH1A1 P00352 3/20 0.42
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP4F2 P78329 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6044544 0.77 MAPT (0.51) CA12CA1CA2CA7CA9
SCHEMBL29175822 0.76 ESR2 (0.42) DRD3DRD2ESR1ESR2
SCHEMBL6854482 0.75 CYP4F2 (0.46) DRD3CA12CA1CA2CA7
SCHEMBL6861924 0.74 CYP4F2 (0.57) DRD3CA12CA1CA2CA7
SCHEMBL6498134 0.74 ESR2 (0.45) ESR1ESR2
SCHEMBL20928770 0.73 KDM4E (0.44) DRD3CA12CA1CA2CA7
SCHEMBL6863568 0.73 CYP4F2 (0.47) DRD3CA12CA1CA2CA7
SCHEMBL876503 0.73 DRD3 (0.54) DRD3CA12CA1CA2CA7
SCHEMBL30583242 0.73 DRD3 (0.54) DRD3CA12CA1CA2CA7
Hydrochloric Acid SCHEMBL6863563 0.73 CYP4F2 (0.46) DRD3CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5756790-A FROM KETONES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-05-26 US disclosed