Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036713 | 0.86 | ESR1 (0.45) | ESR2ESR1MAOB | |
| SCHEMBL6499654 | 0.80 | ESR2 (0.68) | ESR2ESR1CHRNA7PTPN1 | |
| SCHEMBL10262750 | 0.80 | CREBBP (0.41) | ESR2ESR1CHRNA7MAOB | |
| SCHEMBL29196213 | 0.79 | ESR2 (0.45) | ESR2ESR1CHRNA7PTPN1 | |
| SCHEMBL19889287 | 0.79 | ESR1 (0.45) | ESR2ESR1CHRNA7 | |
| SCHEMBL6495993 | 0.78 | CA2 (0.48) | ESR2ESR1MAOB | |
| SCHEMBL29175822 | 0.78 | ESR2 (0.42) | ESR2ESR1PTPN1 | |
| SCHEMBL10506130 | 0.78 | DRD2 (0.42) | — | |
| SCHEMBL8038116 | 0.78 | ESR2 (0.37) | ESR2ESR1CHRNA7PTPN1 | |
| SCHEMBL16900734 | 0.78 | ESR2 (0.78) | ESR2ESR1CHRNA7PTPN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841183-B2 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20020127320-A1 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-1227104-A1 | PROCESSES FOR PRODUCING AND PURIFYING ASPARTAME DERIVATIVES AND PROCESS FOR PRODUCING PRODUCTION INTERMEDIATES | Ajinomoto Co., Inc. (JP) | 2002-07-31 | — | — | EP | disclosed |