Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | PGK1 | P00558 | 1/20 | 0.49 |
| ▸ | PGK2 | P07205 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615046 | 1.00 | ADORA2A (0.55) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8613408 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8613394 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL26489026 | 0.88 | NT5E (0.53) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8612776 | 0.88 | ADORA3 (0.52) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8612786 | 0.88 | ADORA3 (0.52) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL23780561 | 0.84 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8614480 | 0.84 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL8614477 | 0.84 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL23780562 | 0.84 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1PDE2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |